Hi hawk,
Sorry about the forum downtime. Your post was made to the old server, during our transition to a new server.
Yes, you should try reinstalling the program, it may help. What happens, exactly, when you open the software?
You may need to find/delete your TopoFusion.ini file, which should be here:
C:\Documents and Settings\*Your USER NAME*\Local Settings\Application Data\TopoFusion\TopoFusion.ini
Let me know how it goes.